Deep vertical collagen fibrils play a significant role in mechanics of articular cartilage
نویسندگان
چکیده
منابع مشابه
Role of Deep Vertical and Superficial Horizontal Collagen Fibrils Networks in Mechanics of Articular Cartilage
Introduction: Integrity and function of articular cartilage depends directly on networks of collagen fibrils that resist tension and embed the water and matrix resulting in a nonlinear, nonhomogeneous and anisotropic tissue. At the superficial zone, the fibrils are parallel to the articular surface whereas they are rather random in the transitional zone and perpendicular in the deep zone anchor...
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The extracellular framework and two-thirds of the dry mass of adult articular cartilage are polymeric collagen. Type II collagen is the principal molecular component in mammals, but collagens III, VI, IX, X, XI, XII and XIV all contribute to the mature matrix. In developing cartilage, the core fibrillar network is a cross-linked copolymer of collagens II, IX and XI. The functions of collagens I...
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The extracellular framework and two-thirds of the dry mass of adult articular cartilage are polymeric collagen. Type II collagen is the principal molecular component in mammals, but collagens III, VI, IX, X, XI, XII and XIV all contribute to the mature matrix. In developing cartilage, the core fibrillar network is a cross-linked copolymer of collagens II, IX and XI. The functions of collagens I...
متن کاملThe Importance of the Collagen Network Architecture in Articular Cartilage for the Mechanical Loading of Individual Collagen Fibrils
INTRODUCTION The mechanical function of articular cartilage is determined by its high water content and the particular architecture of the collagen network. This network consists of cross-linked fibrils that extend perpendicular from the subchondral bone and curve gradually to a course parallel to the articular surface in the superficial zone [1]. It is thought that loss of the integrity of thi...
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The cartilage which covers the articular surfaces of bones of vertebrate animals has two main functions: the limitation of stress applied to the bone extremities and the provision of the smooth surfaces necessary for the joint to function as an efficient bearing (Kempson, Spivey, Freeman, and Swanson, 1969). To meet these functional demands the cartilage exhibits a combination of physical prope...
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ژورنال
عنوان ژورنال: Journal of Orthopaedic Research
سال: 2008
ISSN: 0736-0266,1554-527X
DOI: 10.1002/jor.20537